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Pat Sajak’s daughter Maggie goes public with Savannah Bananas star Jackson Olson
Pat Sajak’s daughter Maggie goes public with Savannah Bananas star Jackson Olson
Hegseth announces end to military flu vaccine requirement: ‘We will not force you’
Study Shows Some Humans Are Evolving To Be 'Foxier'
Authored by David Randall via RealClearScience,
The latest report from David Reich’s genetics lab at Harvard is that “Ancient DNA reveals pervasive directional selection across West Eurasia.” In other words, humans have been continuing to evolve in Europe and the Middle East for the last 10,000 years, with significant effect. Reich’s paper broadly substantiates the thesis of Gregory Cochran and Henry Harpending’s The 10,000 Year Explosion: How Civilization Accelerated Human Evolution. Civilization hasn’t ended biological evolution, but proceeds alongside it.
Reich’s genome-wide association study (GWAS) indicates that West Eurasians have increased or reduced their vulnerability to a variety of ailments. Genetic changes have rendered them less susceptible to leprosy, rheumatoid arthritis, bipolar disorder, and schizophrenia, and moreso to coeliac disease and gout. At the same time, there has been positive selection for fair skin, red hair, and intelligence, and negative selection for male-pattern baldness. In summary, West Eurasians have grown foxier, as the arc of their genetic history bends toward fluffy ginger genius.
Reich’s conclusions are pretty likely to hold water. Too many scientific and social scientific fields have been affected by the irreproducibility crisis of modern science. The worst-hit disciplines use far too loose a definition of statistical significance, p < 0.05. Genome-wide association studies, by contrast, tend to use the extraordinarily tighter standard of p < 5 × 10^ −8. Reich lab’s research includes a variety of different standards of statistical significance, including some that are only of p < 8.9 × 10^ −5. That standard is orders of magnitude more reliable than most research.
The data Reich’s lab can work with, after all, is remarkably bounteous. As the researchers wrote:
[W]e increased power through a 14-fold increase in sample size, driven by 10,016 ancient individuals for whom we report new data, which combined with previously reported data yields a dataset of 15,836 people spanning 18,000 years … The final dataset included 8,074,573 SNPs [single-nucleotide polymorphisms] and 1,665,051 insertions or deletions (indels) on chromosomes 1–22.
Science only can advance on sure foundations when you’re reasonably likely the research will hold up. Sociology, psychology, any discipline where you cannot work with millions of pieces of data, cannot be expected to match GWAS levels of rigorous statistical significance. But, as many scientists have proposed, p < 0.01 or p < 0.005 are not impossible goals, even for disciplines less rich in data. Reich’s peers in other disciplines should look at his work and consider the benefits of reasonable certainty that a paper you publish actually says something true.
Americans in general might also take Reich’s work as a prompt to reconsider our various moratoria on using American Indian biological data to provide gene samples. Reich’s report on West Eurasian genetic data presumably is only a beginning. We may expect reports to come on East Eurasians, Sub-Saharan Africans, Aboriginal Australians, Khoisan in South African, American Indians in Latin America—reports on people all over the world.
Except on the American Indians of the United States.
Our legal, regulatory, and cultural inhibitions mean that there will be an enduring blank spot in the knowledge we gain from the genetics revolution—knowledge which will aid not only paleogenetic research but also advances in medicine tailored to each individual’s DNA. American Indians might be the last people on Earth to benefit from such advances in genetically individuated medicine if we continue to veto researchers’ use of American Indian genetic and paleogenetic data.
Science funders also should note that science proceeds by joint work in many disciplines and isn’t just a high-tech plaything. The Reich lab’s research depended not least upon “10,016 ancient individuals for whom we report new data.” Those individuals didn’t just show up in laboratories by magic. They came there by careful work by archaeologists, by intelligent observations from interested amateurs, by hard and careful work in caves, in ancient graves, and in sudden gullies opened by rainstorms. Brawn, physical finesse, and something of the Indiana Jones spirit of adventure were as important for making this research possible as microscopes and microchips. Dear Mr. and Mrs. Moneybags: no dig, no data. We all should remember that, too.
David Randall is the Director of Research at the National Association of Scholars.
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US Throttles Intelligence-Sharing With South Korea After Nuclear Disclosure Row
The United States has reduced intelligence sharing with South Korea pertaining to eavesdropping on North Korea following an alleged leak tied to sensitive information, according to local media reports.
But it is a major allegation that the government has dismissed as 'absurd'. South Korean President Lee Jae Myung took to X at the start of this week to write, "Any claim or action based on the premise that Minister Chung ‘leaked classified information provided by the US’ is wrong."
Bloomberg, citing Yonhap and others, wrote that "South Korean media reported that the US is limiting intelligence sharing on North Korea with Seoul after Unification Minister Chung Dong-young publicly identified North Korea’s uranium enrichment facility in Kusong last month."
AFP/Getty ImagesWashington reportedly began limiting access earlier this month to certain intelligence linked to North Korea’s technological capabilities, widely believed to involve aspects of its nuclear program, according to Yonhap News.
"It's true that the US side has been restricting sharing parts of North Korean intelligence collected through satellites from early this month," a senior military official said. "(The restricted sharing of intelligence) is related to information regarding parts of North Korea's technology."
Some 28,500 US troops are permanently stationed in South Korea, and the US is a longtime military partner going back to the Korean War of the mid-20th century. US intel-sharing has always heavily assisted Seoul with missile warning data and satellite surveillance.
The whole rare episode stems from remarks by South Korea's Unification Minister Chung Dong-young during a March 6 parliamentary session, when he openly identified Kusong as a third North Korean uranium enrichment site alongside facilities at Yongbyon and Kangson.
The speech marked a first official acknowledgment by Seoul of the Kusong site, which then triggered backlash from Washington, featuring complaints from US officials through diplomatic and military channels who viewed it as a potential exposure of sensitive, possibly shared intelligence.
Chung in turn rejected the accusations, framing his remarks as all based in open source and public data which can be found through research reports.
Pyongyang is probably enjoying the spectacle, having long vehemently denounced the US presence on the Korean peninsula, also given the sporadic docking of a US nuclear submarine. This is a very rare moment of tensions among allies on the Korean peninsula.
Tyler Durden Wed, 04/22/2026 - 04:15Yankees’ Luis Gil blanks Red Sox without best stuff and velocity
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Coinbase Now Lets UK Users Borrow Against Their Bitcoin And Ethereum
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Coinbase launched crypto-backed USDC lending for U.K. users on Monday.
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Bitcoin holders can borrow up to $5 million in USDC, with Ethereum-backed loans capped at $1 million.
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The service uses Morpho, an open-source lending protocol on Ethereum layer-2 network, Base.
Crypto exchange Coinbase has expanded its lending service, now allowing U.K. customers to borrow USDC stablecoins using their Bitcoin or Ethereum holdings as collateral.
The service operates through Morpho, an open-source lending protocol on Base—the Coinbase-backed Ethereum layer-2 network—that powers Coinbase's crypto-backed loans.
U.K. users can pledge cryptocurrency as collateral to access USDC liquidity without liquidating their digital assets.
Borrowing limits vary by collateral type.
Bitcoin holders can access up to $5 million in USDC, while Ethereum-backed loans top out at $1 million, depending on the amount pledged.
Coinbase first launched the crypto-backed loan service in the United States in January 2025, and said it has facilitated $2.17 billion USDC in loan originations as of April 14.
The lending product adds to Coinbase's growing U.K. service portfolio.
The exchange introduced decentralized exchange trading for U.K. users just last week, and previously launched savings accounts in November 2025.
These offerings followed Coinbase's February 2025 FCA registration, which enabled the firm to expand regulated services in the market.
“Crypto-backed loans are part of Coinbase’s efforts to build the number one financial app in the U.K.,” said Coinbase U.K. CEO, in a statement.
“We want to be the best place for U.K. consumers to invest, manage and grow their money.”
Coinbase (COIN) shares on the Nasdaq are down about 1% on the day at a current price above $204, though they’re up nearly 17% over the last week amid broader crypto and stock market recoveries.
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China Loads Up On US Chip Tools Via Southeast Asia Amid Supply Chain Shift
China's imports of chipmaking equipment from Malaysia and Singapore rose sharply in 2025 to surpass those from the US, which sank to an eight-year low, an analysis by Nikkei Asia has found - even as American companies remain a vital source of advanced tools for the country.
While the Netherlands and Japan remain China's primary foreign sources of critical semiconductor manufacturing machines by shipment origin, imports from the two Southeast Asian countries reached record levels: $5.7 billion for Singapore, up more than 17% year over year, and $3.4 billion for Malaysia, more than double the 2024 figure.
Direct imports from the US, meanwhile, declined more than 34% to about $2 billion, the lowest level since 2017, according to Chinese customs data. The decline was to be expected following President Trump's return to the White House, as he sharply limited access of US semiconductors to China, although tensions began earlier. Since Trump's first term and during the subsequent Biden administration, the US has raised tariffs and imposed fresh export controls aimed at slowing China's advances in chipmaking technologies for defense, space and artificial intelligence applications.
Despite the decline, the Chinese market remained a critical revenue source for leading US chip equipment makers last year. Applied Materials, Lam Research and KLA all earned more than 30% of their total sales from China in fiscal 2025.
Charles Shi, a veteran semiconductor analyst with Needham & Co., told Nikkei Asia that the uptick in China's imports from Southeast Asia is mainly due to the large number of U.S. chip equipment makers expanding manufacturing capacity in the region to better serve non-U.S. clients.
"Lam Research is building significant manufacturing capacity in Malaysia as they work to meet growing equipment demand beyond what their U.S. manufacturing capacity can serve," Shi said. "Singapore has been a popular destination for [the] U.S. equipment industry to go overseas. For example, both Applied Materials and KLA have been manufacturing in Singapore."
The three top U.S. chip tool makers generated nearly $19 billion in combined revenue from China in fiscal 2025, significantly exceeding figures implied by customs data based on where shipments originated from and underscoring the effectiveness of American vendors' production diversification strategies. Nikkei Asia first reported their production shift toward Southeast Asia in early 2023.
For ASML of the Netherlands, China's share of revenue came to 29.1% in 2025, while the figure for top Japanese chip tool maker Tokyo Electron was more than 40% for fiscal 2025.
Anticipating major chip wars, over the course of 2020 to 2025, China's accumulated chip tool imports from Japan reached more than $42 billion, followed by the Netherlands' $35 billion . Japan is home to many top chip equipment makers such as Tokyo Electron, Screen Semiconductor Solutions and Ebara, while the Netherlands has the world's largest chip equipment maker, ASML, as well as key suppliers such as ASM, an atomic-level deposition tool specialist, and Besi, a maker of advanced chip packaging tools.
Meanwhile, China's domestic chipmaking equipment makers are experiencing a once-in-a-generation surge in growth, driven by Beijing's push to foster homegrown tools and reduce reliance on foreign technologies. Top suppliers all reported record revenue and profits for 2025, led by Naura, Advanced Micro-Fabrication Equipment Inc. China (AMEC), ACM Research and Piotech.
Naura, China's answer to Applied Materials, has seen its revenue balloon from 6.05 billion yuan ($887 million) in 2020 to 27.14 billion yuan in the first three quarters of 2025. Revenue for AMEC skyrocketed more than 400% from 2020 to 2025. Piotech, a thin-film deposition chip tool specialist, has seen its revenue grow 13 times between 2020 and 2025.
Shi of Needham said China has made good progress in fostering local chip tool makers, but internal competition is intensifying. "While leading domestic equipment companies are still posting strong revenue growth, there are indications that their margin performance is deteriorating," Shi said of Chinese chipmaking companies. "We believe intensifying domestic competition might have forced domestic equipment companies to 'race to the bottom' by undercutting each other's prices."
With China's equipment suppliers becoming more competitive in recent years, US policymakers are seeking to further close loopholes in export rules. In April, bipartisan lawmakers introduced the MATCH Act, which calls on "multilateral allies" to coordinate more closely in aligning and tightening export restrictions across key segments of the chipmaking equipment industry. These measures would further target critical "chokepoint" components and machinery, as well as shipments to leading Chinese memory and logic chipmakers, including CXMT, YMTC, SMIC and Hua Hong.
"Chinese tool companies on the Entity List are unable to get access to U.S. parts, but there are many parts that Europe and Japan can backfill, and that's the conundrum that we find ourselves in today," Kevin Kurland, a former official at the U.S. Department of Commerce and current senior advisor at Beacon Global Strategies, told Nikkei Asia. "If controls don't get aligned multilaterally with allies, U.S. controls can undercut American companies' competitiveness while allowing Chinese companies to continue to function and operate - a lose-lose outcome.
Alex Rubin, a former CIA China analyst and visiting fellow at the Hoover Institution, told Nikkei Asia that "component export controls definitely make sense."
"It's very similar to what we are seeing in commercial aviation: China is assembling the finished C919 aircraft, but is sourcing parts from U.S. and European suppliers. Chinese companies are trying to compete with Boeing and Airbus, while sourcing from a similar supply chain," Rubin said.
While China is still massively sourcing foreign chip tools, its ultimate goal is self sufficiency, industry sources say.
While durability, reliability and performance may not be at the same level, "for every foreign chipmaking tool, material and component you can think of, you could find Chinese versions," said an executive with a Taiwanese chipmaking tool who participated in the Semicon China industry event in late March. "Chinese chipmakers will continue to buy foreign solutions while they can, but there's no doubt about the country's will to increase the use of homegrown suppliers."
"China is adopting a two-way approach: developing homegrown tools while continuing to purchase foreign equipment whenever possible. Since imported tools often offer better performance, they are still buying aggressively -- and even repurposing consumable parts from one piece of equipment to repair other chipmaking machines," another chip industry executive with knowledge of the matter told Nikkei Asia.
A third executive with a Chinese chipmaking tool supplier told Nikkei Asia that the aggressive expansion plans by Chinese logic and memory chipmakers have given local vendors more opportunities to break into and secure a position in the domestic supply chain.
Nikkei Asia was the first to report that Chinese top chipmakers led by SMIC, Hua Hong and Huawei-linked chipmakers are aiming to aggressively expand advanced chip production capacity, including on the performance level of 7-nanometer or even 5-nm technologies, to support the rise of domestic AI chip developers. Meanwhile, top Chinese memory chip producers CXMT and YMTC are launching their largest expansions in response to the unprecedented global memory crunch amid the AI boom, Nikkei revealed in early February.
American allies such as the Netherlands and Japan have already introduced rules to align with U.S. export controls, but policymakers in Washington feel those restrictions are still much too loose. The U.S. has imposed multiple rounds of regulation on exports to China and has added many leading Chinese chip equipment suppliers and chipmakers to its Entity List.
The MATCH Act, if passed, could further limit global vendors' ability to supply critical tech to China. The bill targets some older - though still critical - generations of chipmaking machines as well as components, both of which can be chokepoints for China's efforts to build up its domestic chip industry. Introduced in early April, the bill still needs to go through the legislative process, and it remains unclear how the Netherlands, Japan and other countries would respond to any diplomatic pressure to comply. For example, only ASML in the Netherlands and Canon and Nikon in Japan can produce commercially viable lithography machines -- an area where China continues to face significant challenges.
Tyler Durden Wed, 04/22/2026 - 02:45