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On Wednesday, the Duchess of Sussex teased an As Ever launch "inspired by" the $14 million California mansion she and Prince Harry purchased in 2020.

Pike, who would have been the first woman executed in Tennessee in more than 200 years, somehow survived the double dose of the highly potent sedative, Pentobarbital.

“It’s a miracle that my son is alive.”

Amazon Secures 20 Years Of Nuclear Power From Constellation As Goldman Sees Industry-Wide Win

Goldman analyst Carly Davenport views Amazon's nuclear power deal with Constellation Energy as "positive for industry broadly" as the "Powering Up America" theme and nuclear theme continue as Big Tech scrambles for the cleanest form of stable power to fuel data centers chip stacks. 

Davenport said Constellation Energy's 20-year deal to supply Amazon with 690 megawatts from Maryland's Calvert Cliffs nuclear plant is positive for both the utility and the broader power complex. 

Calvert Cliffs has two nuclear reactors, with a combined generating capacity of about 1,790 megawatts, enough to power 1.3 million homes. The deal unlocks power to Amazon's data centers across the 13-state grid overseen by PJM Interconnection. 

The deal also supports more than $3 billion in infrastructure investment at the nuclear power station, including upgrades adding 190 megawatts of generating capacity between 2030 and 2032. It also provides Constellation with revenue certainty. 

Davenport explained the deal:

Terms of the agreement: CEG and Amazon signed a 20-year PPA for nuclear power at the Calvert Cliffs Clean Energy Center, Maryland’s largest carbon-free energy facility and only nuclear plant.

Amount of capacity: The PPA is for 690 MW of total capacity, which includes a 190 MW of uprates scheduled to come online between 2030 and 2032.

Capital commitment: The agreement enables $3 bn+ in infrastructure investment to fund state-of-the-art upgrades across the entire 1,790 MW facility.

PJM implications: All electricity from Calvert Cliffs will continue to flow into the PJM regional grid. The parties have entered a separate but related retail supply agreement to support Amazon’s operations across the 13-state PJM market.

Beyond the agreement: The company highlighted the contract provides the long-term revenue certainty necessary for Constellation to pursue a 20-year license extension for the facility and explore further development of new clean energy power plans on-site.

Financial implications: While the release provides no color around pricing, we would point to the company’s disclosures which include a sensitivity on FCFbG upside from data center PPAs. CEG noted that 1 GW Nuclear PPA at a $20-$50/MWh premium to the PTC floor would translate to $125M-$325M FCFbG upside, implying FCFbG uplift of ~$86mn-$224mn if applied to the total 690 MW contract with Amazon.

Davenport added, "We view the PPA announcement as a solid update for the company and industry especially given it is for capacity in PJM, which has been a challenging environment recently due to regulatory uncertainty within the market, and investor confidence has been low in incremental data center PPAs being announced in the near term." 

"This agreement demonstrates how private investment can strengthen critical energy infrastructure," said Constellation CEO Joseph Dominguez.

Because of the AI data center buildout, nuclear power is getting new life, and grid upgrades will help buffer the fragile PJM region during peak demand. 

More importantly, the added capacity may help Maryland after years of 'climate-friendly' policies transformed the grid into a mess that collided with the era of data centers and electrification. One has to ask what the Democrat-run state was thinking over the years as it focused on everything but preparing the state for the next evolution of the modern economy. 

Constellation shares were up nearly 4% in pre-market trading. Davenport maintains a "Neutral" rating on the utility, with a 12-month price target of $305.

Tyler Durden Thu, 10/01/2026 - 08:15

Willson Contreras provided one of the few good Red Sox swings in this embarrassing showing against the Yankees and then took another postgame whack at his team.

"I don't think I've ever had more opinions on myself in my life than I have in this last year," the country music singer said at a recent concert.

"I don't think I've ever had more opinions on myself in my life than I have in this last year," the country music singer said at a recent concert.

Lilly's "Incredible Hulk" Obesity Combo Delivers Record 23% Weight Loss In Diabetics

Eli Lilly's experimental combination of eloralintide and Mounjaro delivered average weight loss of up to 23% in people with diabetes, strengthening the company's competitive edge against Novo Nordisk in the obesity and diabetes treatment market.

Participants who received the highest dose lost an average of 54 pounds over 48 weeks. Their A1C, a measure of average blood sugar, fell 2.9 percentage points from a baseline of 8.1%, with up to three-quarters reaching normal blood sugar levels, according to Bloomberg.

"This could open up even a next frontier in weight loss," Ken Custer, president of Lilly's cardiometabolic unit, stated.

Custer said the study sets a "new, even higher bar" but cautioned against comparing different studies.

Lilly shares rose as much as 2.6% earlier today before paring gains. Year to date, shares are up a little more than 10%, while competitor Novo Nordisk has slumped more than 20%.

The Study

The Phase 2b trial, announced by Lilly Wednesday and presented at the European Association for the Study of Diabetes (EASD) meeting in Milan, randomized 367 adults with obesity or overweight and type 2 diabetes in the US and Argentina to placebo, eloralintide alone, tirzepatide alone, or one of four combinations of the two. Tirzepatide is the active ingredient in both Mounjaro and Lilly's obesity shot Zepbound. Lilly calls the combination EloraTZP.

Eloralintide mimics amylin, a hormone the pancreas releases alongside insulin that slows digestion and signals fullness to the brain. Tirzepatide hits two gut hormone receptors, GIP and GLP-1, so the combination works on three appetite and blood sugar pathways at once.

The results at 48 weeks, from an average starting weight of 232.4 pounds:

Arm Weight change Pounds A1C change Eloralintide 9 mg + tirzepatide 15 mg -23.3% -54.1 -2.9 Eloralintide 6 mg + tirzepatide 10 mg -19.9% -46.2 -2.6 Eloralintide 6 mg + tirzepatide 5 mg -19.4% -45.1 -2.7 Eloralintide 3 mg + tirzepatide 5 mg -13.2% -30.7 -2.2 Tirzepatide 15 mg alone -14.8% -34.4 -2.4 Eloralintide 6 mg alone -12.3% -28.6 -1.4 Placebo -3.0% -7.0 -0.3

Source: Eli Lilly. Efficacy estimand, i.e. assuming all participants stayed on treatment.

In other words, adding eloralintide to the top dose of Mounjaro bought an extra 20 pounds of weight loss. Oddly, the highest dose of eloralintide on its own (9 mg) did worse than the 6 mg dose, at 11.1%.

Weight loss is typically harder to come by in diabetics, which is what makes the number stand out. Analysts at Citi wrote that the 23.3% figure is "comparable to tirzepatide in patients without T2D" and came in "comfortably above our 17% bar." For comparison, Lilly's triple-hormone shot retatrutide produced 20.8% weight loss in diabetics in its Phase 3 TRIUMPH-2 trial, and that took 80 weeks.

Study investigator Julio Rosenstock offered a very colorful description of the new GLP-1 wonder drug. Having nicknamed Mounjaro "King Kong," with retatrutide already claiming "Godzilla," Rosenstock called the new combination the "Incredible Hulk." Rosenstock, a University of Texas diabetes researcher, coined the first two in 2023: "We know that tirzepatide (Mounjaro) is the King Kong of the GLP-1s. And when I look at retatrutide, I think that there is no question that Godzilla is smiling."

The Catch

Rosenstock cautioned that not all patients need to lose that much weight. At the highest dose, 27% of participants stopped taking the drug because of side effects. More than four-fifths reported a side effect of some kind, with roughly half experiencing nausea.

Across the four combination arms, Lilly reported discontinuation rates due to adverse events of 10.8% to 27%, versus 2.9% for tirzepatide alone. The side effects were mostly gastrointestinal and hit hardest during dose escalation. Citi's analysts blamed starting both drugs at once and said a gentler Phase 3 titration "could preserve efficacy while improving adherence." Custer told CNBC Lilly will adjust the dosing, "and we expect that we'll end up with a very favorable balance of efficacy and tolerability."

Lilly vs. Novo

The results add competitive pressure on Novo, which pioneered the approach with CagriSema, a combination of its amylin treatment cagrilintide and semaglutide, the active ingredient in its blockbuster Wegovy.

That drug has already been bloodied by Lilly. In February, CagriSema failed to prove it was even as good as Mounjaro in the head-to-head REDEFINE 4 trial, with 23% weight loss after 84 weeks versus 25.5% for tirzepatide. Novo filed CagriSema with the FDA in December 2025 and expects a decision by late 2026.

Novo also lost the fight for the next amylin drug. In November, Pfizer outbid it for Metsera in a roughly $10 billion bidding war over the biotech's monthly amylin candidate. Meanwhile Mounjaro overtook Merck's Keytruda as the world's best-selling drug in the first quarter, with $8.7 billion in sales.

Lilly plans to begin late-stage studies of the new combination by year-end, using a single co-formulated injection rather than the two separate shots used in this trial. Eloralintide is already in Phase 3 on its own, after producing up to 20.1% weight loss in non-diabetics in a 48-week Phase 2 study.

Tyler Durden Thu, 10/01/2026 - 08:00

Bet $20, get $350 in FanCash with Fanatics Sportsbook promo code NYPOST350.

The Big East coaches are high on the St. John’s backcourt and expect the Johnnies to remain near the top of the league. 

Happy October 1st!

Boone managed circles around Boston's Chad Tracy in the two-game sweep in The Bronx. That is indisputable.

Canada Has A Ukrainian Blindspot

Authored by Ted Snider via The Libertarian Institute

On September 10, Ukrainian President Volodymyr Zelensky landed in Canada where he and Canadian Prime Minister Mark Carney signed a 100-year partnership "elevat[ing] the relationship between their countries into a Comprehensive Strategic Partnership and confirming their aligned nature."

Canada already has a special relationship with Ukraine. Before the war, Canada had the largest Ukrainian community in the Ukrainian diaspora with 1,209,805 Ukrainian-Canadians. Canada is the fifth largest financial contributor to Ukraine after only the United States, the European Union, Germany, and the United Kingdom with over $16 billion in military, financial and humanitarian aid.

Carney said that “Canada will always stand in solidarity with Ukraine” and that “there is no qualification to our commitment.” There is little wrong with that: Ukraine was invaded by Russia and taken advantage of by the West.

But there are two problems with the Comprehensive Strategic Partnership. The first is practical.

Since Russia invaded Ukraine in 2022, Canada has contributed $8.5 billion in military support to Ukraine. The Comprehensive Partnership includes a joint declaration on defense and security co-operation. During the official visit, Carney announced new investments to support Ukraine’s defense, including $350 million for interceptor missiles for air defence.

The practical problem is that Ukraine is black hole into which money intended for defense disappears. This is a problem well known to Ukraine’s partners who, nonetheless, keep pouring money in with a blind eye to the problem. Earlier this month, following close on the heels of a U.S. $100 billion European Union loan to Ukraine, Kiev surprised the European Union with a request for an additional $27 billion to address a shortfall that was difficult to explain. The request “unsettled” European officials, some of whom privately worried “whether money is being spent efficiently or whether needs are being overstated.”

A recent New York Times investigation found that seven of Ukraine’s ten top military contractors continued to be awarded contracts after Kiev knew they were facing investigations for fraud, corruption, or failure to deliver on deals they were paid for. Eighteen companies won contracts despite defaulting on previous ones. Millions were thrown away by inexplicably, and conveniently, awarding contracts to the highest bidder. Government audits show that in one year of the war alone, Ukraine lost $1.2 billion in U.S. foreign aid to “fraud, waste and mismanagement.” Sending hundreds of millions more to Ukraine sounds great. But to whom will it go?

There is a second problem with the 100-year Comprehensive Partnership that is deeper. Carney said the Strategic Partnership is based on the two countries “aligned nature.” But there are important aspects that do not align.

Canada is a federalist country that officially recognizes more than one culture and language. The Carney administration recently walked away from negotiating a trade agreement with the United States partly in defense of its sovereign right to protect French culture, French language, and its official bilingualism. Ukraine has been locked in a civil war since 2014 to protect the opposite: a monist vision of Ukrainian society that rejects federalism and recognizes only one culture as Ukrainian while suppressing the language, culture, and religion of ethnic Russian citizens of Ukraine in Crimea, the Donbas, and the southeast. It specifically denies the pluralist alternative that is a defining feature of Canadian identity. Rather than aligning in their natures, in this essential aspect, the two countries are the antithesis of each other.

Canada has confronted this blind spot before. In 2023, Yaroslav Hunka received two standing ovations in Canada’s Parliament as “a Ukrainian Canadian war veteran from the Second World War who fought for Ukrainian independence against the Russians” and as “a Ukrainian hero and a Canadian hero,” despite having served in the 14th Waffen Grenadier Division of Adolf Hitler’s SS.

Carney insisted that “Canadians understand in our bones the importance of your struggle” and explained that the reason “there is no qualification to our commitment” to Ukraine is “because your cause—freedom, democracy, sovereignty—is our cause.”

A standing ovation from the Canadian parliament and then he also got a personal meeting with Trudeau and Zelensky.

'Waffen SS' veteran Yaroslav Hunka must feel very loved in Canada...... pic.twitter.com/5BjwrWsWtS

— Richard (@ricwe123) August 17, 2025

It may be “our cause,” but the historical record is less clear that it is their cause. Zelensky has formally banned eleven opposition parties, including the Opposition Platform for Life party that was once the second largest party in the Ukrainian parliament, though they all condemned Russia’s invasion and contributed to Russia’s defence.

He has restricted freedom of information, unifying all television sources into a single source of television news, and increased the censorship powers of the state over print and online media.

The Ukrainian Orthodox Church, Ukraine’s largest church organization, has been banned by Zelensky though Ukraine’s constitution protects freedom of religion, despite that the Primate of the UOC expressed the church’s loyalty to Ukraine and condemnation of Russia’s invasion.

Cultural and linguistic rights for minorities have fared no better than political and religious rights and freedom of expression. Pursuing the monist interpretation of Ukraine, Zelensky has gone down a path of abolishing any hint of Russian culture. Legislation has erased the Russian language, making Ukrainian the sole language of government, schools, universities, culture, publishing and media.

It is fine for Canada to “stand in solidarity with Ukraine.” But we should not be blind to Ukraine’s struggles and challenges. If Ukraine is to avoid civil war after the war with Russia and if Ukraine is to have a chance of joining the European Union and orienting toward the west, they, too, are going to have to confront these challenges.

Tyler Durden Thu, 10/01/2026 - 07:40

The president wants AI to be called super intelligence - or SI - the same initials used by Slovenian domains.

Ben Affleck, Kerry Washington, Chris Evans, and Anya Taylor-Joy lead the way this October on Netflix.

Sen. Marsha Blackburn sued former special counsel Jack Smith and the Justice Department in Tennessee federal court Wednesday.

The flydubai staffer accused of trying to hijack a plane carrying 174 people to Israel by stabbing the lead pilot was a religious extremist who refused to shake hands with women, according to a colleague.

Home prices across an Eastern swath surged 6.3% year over year, leading the nation even as housing markets elsewhere cool.

"Yes, could he fix the "f--king BQE, please?" Davidson said in a clip shared on the show's Instagram page.

The actress divulged to Page Six last week that her residuals were "negative," quipping that it cost her "more to print the check.”